Jeffrey Dean Morgan was born in Seattle, Washington. At school, he played football and captained the basketball team. He went on to play basketball at Skagit Valley College before being sidelined by injury.
Starting with Uncaged (1991), Morgan has appeared in over 25 feature films. However, the bulk of his work has been in television. He was the star of the 1996–1997 television series The Burning Zone; his character, Dr. Edward Marcase, appeared in 10 out of 19 episodes that season. In 2005 and 2006, Morgan simultaneously appeared in three television series: in the CW series Supernatural as John Winchester, in a recurring role on ABC’s Grey’s Anatomy as heart transplant patient Denny Duquette, and as Judah Botwin in two episodes of the Showtime series Weeds. He has also guest-starred in a number of television series, including ER; JAG; Walker, Texas Ranger; Angel; CSI: Crime Scene Investigation; Sliders; The O.C.; and Monk. In 2007, Morgan was cast in a proposed project by Grey’s Anatomy creator Shonda Rhimes. The series, tentatively titled “Correspondents”, was to have started production in summer 2007. ABC instead picked up a spin-off of Grey’s Anatomy, called Private Practice, that was also created by Rhimes. As a result, “Correspondents” was shelved. Another 2007 film starring Morgan is The Accidental Husband, which finished filming in New York City in March 2007 and was not released on DVD until 2009.
Morgan starred in the thriller The Resident and the drama film Days of Wrath in 2008.
In 2009, Morgan portrayed The Comedian, a cigar-chomping antihero, in Watchmen, based on Alan Moore’s graphic novel. The same year, Morgan appeared in Taking Woodstock, and played Clay in a comic book movie adaptation of The Losers.
Morgan appeared in the Texas crime thriller Texas Killing Fields as a homicide detective in 2011. The following year, Morgan starred in the television drama series Magic City, which centered on mob life in 1950s Miami. The same year, Morgan appeared in the horror thriller The Possession, and the war film Red Dawn. It was announced in January 2014, that Morgan had been cast in the lead role in Jonás Cuarón’s Desierto.
In November 2014, Morgan was cast as Joe DiMaggio opposite Kelli Garner as Marilyn Monroe in The Secret Life of Marilyn Monroe, a Lifetime four-hour miniseries based on J. Randy Taraborrelli’s book of the same name.
In 2015, Morgan portrayed Deaf Smith in Texas Rising, a five-part mini-series which aired on the History Channel. Also in 2015, he became a regular cast member for season 2 of the CBS sci-fi drama Extant.He appeared in an role in Batman v Superman: Dawn of Justice, as Bruce Wayne’s father, Thomas Wayne.
He played the character of a freelance investigator Jason Crouse in the popular TV show The Good Wife. Afterward, Morgan portrayed the character Negan on the AMC TV series The Walking Dead. He made his first appearance in the sixth-season finale and serves as the primary antagonist of the seventh season.